Ratio-specific preparations80:20
Estriol / estradiol combinations
Review capsule and cream listings separately. The ratio, total amount and component amounts should be confirmed for the exact preparation.
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Hormone health · Clinic product catalog
Bi-estfor Your Clinic.
Explore estriol and estradiol combination preparations. Review the stated ratio, total strength, dosage form and pharmacy details before selecting a product.
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Your product options
The ratio is part of the specification.
Thirteen catalog entries include 80:20 and 50:50 naming, capsules and topical creams. Confirm which ingredient each ratio refers to and the individual component strengths.
Distinct ratio listings50:50
Separate formulation review
Optimal lists 50:50 preparations in several amounts. Some source names do not establish the dosage form; confirm before selection.
Explore pharmacy listingsIllustrative packaging. Actual appearance and packaging vary.
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13 source entries. Open a pharmacy to review its listings. Repeated or similar names do not establish distinct products or current availability.
Emerald1 listings
| Source preparation / review note | Listed strength / concentration | Package |
|---|---|---|
| Biestrol 80/20mgSource ratio / amount wording requires confirmation | Confirm ratio and component strengths | Confirm package quantity |
Boothwyn2 listings
| Source preparation / review note | Listed strength / concentration | Package |
|---|---|---|
| ESTRIOL/ ESTRADIOL (BIEST 80:20) (IR)Potential overlap with the other Boothwyn entry; verify exact product | Confirm exact specification | Confirm package quantity |
| Estriol/Estradiol (Bi-est 80:20) 0.8mg/0.2mg (1mg) IR Capsule (90 count) | Estriol 0.8 mg / estradiol 0.2 mg (1 mg total) | qty 90 |
Optimal10 listings
| Source preparation / review note | Listed strength / concentration | Package |
|---|---|---|
| BI-EST (50/50) Capsule 5MG | 5MG | Confirm package quantity |
| BI-EST (80/20) Capsule .625mg | 625mg | Confirm package quantity |
| BI-EST (80/20) Capsule 1.25MG | 1.25MG | Confirm package quantity |
| BI-EST (80/20) Capsule 2.5MG | 2.5MG | Confirm package quantity |
| BI-EST (80/20) Capsule 5MG | 5MG | Confirm package quantity |
| BI-EST (80/20) Capsule 6mg | 6mg | Confirm package quantity |
| BI-EST (80/20) Topical Cream 2mg/mL | 2mg/mL | 30ml |
| BI-EST (80/20) Topical Cream 3mg/mL | 3mg/mL | Confirm package quantity |
| Bi-est 50/50 (Immediate Release) 2.5MGDosage form requires confirmation | 2.5MG | Confirm package quantity |
| Bi-est 50/50 (Immediate Release) 2mgDosage form requires confirmation | 2mg | Confirm package quantity |
Before you order
The product details that matter.
Review the exact product with the responsible pharmacy before submitting an order.
- Product family
- Estriol and estradiol combination preparations
- Listed ratios
- 80:20 and 50:50 — confirm component order
- Listed forms
- Capsules and topical creams; some entries need form confirmation
- Catalog pharmacies
- Emerald, Boothwyn and Optimal
- Strength review
- Review total strength and individual component amounts
- Regulatory context
- A compounded preparation is not FDA-approved
From access to repeat orders01 / ACCESS 02 / REVIEW 03 / ORDER 04 / REORDER
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Review Bi-est options.
Review the preparation, pharmacy information and account pricing.
Complete checkout.
Confirm your cart, order details and applicable requirements.
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Use saved carts and order history for repeat purchasing.
Participating pharmacies retain prescription review, dispensing and fulfillment responsibilities.
Product contextClinical information,
Clinical information,
with clear sources.
The treating clinician determines suitability and prescribing. Review the exact product’s labeling and pharmacy information.
Bi-est is a naming convention for estriol/estradiol combinations, not a single standardized product. A ratio does not specify the total amount, route or package.
Avoid assumptions from “bioidentical” wording.
FDA does not have evidence that compounded bioidentical hormone therapy is safer or more effective than approved therapy. FDA also states that evidence does not establish estriol-containing drugs as safe and effective or a safer form of estrogen. FDA: hormone therapy questions
Confirm the regulatory status of the exact preparation. Compounded drugs are not FDA-approved and do not undergo FDA premarket review for safety, effectiveness or quality. FDA: compounded drug information
Sources checked October 19, 2026. This page provides product information, not diagnosis, treatment selection, dosing or administration instructions.
Useful answers
Bi-est ordering FAQs.
Does an 80:20 ratio identify the complete preparation?
No. Confirm the order of ingredients, amount of each ingredient, total strength, dosage form, route and package. A ratio alone does not establish equivalent preparations across pharmacies.
How many pharmacy entries are represented?
This page represents 13 source entries. Some names may overlap; confirm the exact product and current availability through your approved account.
Are strengths and concentrations patient doses?
No. Product amounts, concentrations and package quantities describe different specifications. The clinician and dispensing pharmacy determine the prescription and instructions.
Are products from different pharmacies interchangeable?
Interchangeability is not established by a shared ingredient name, matching concentration or release abbreviation. Review each complete formulation and label.
Are all products on this page FDA-approved?
No approval status is established by catalog inclusion. Compounded preparations are not FDA-approved. Confirm the exact product and regulatory status with the pharmacy.
Can patients place orders directly?
Ordering and account pricing are available to verified, approved clinic accounts. Patients should discuss prescriptions and treatment with their clinician.
What should my clinic check before reordering?
Review the current ingredient list, strength units, dosage form, route, release characteristics, package, availability, storage and applicable pharmacy requirements.
How can my clinic contact CoreLink?
Email info@corelinkpharm.com for platform and account questions. Contact the pharmacy for product-specific information.
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